# R6 | openai/gpt-5.4-mini | run 2

## Prompt

Summarize the main documented health effects of the Mediterranean diet in 4-5 points, with a citation for each claim.

## Response

The Mediterranean diet is most consistently linked with lower cardiovascular risk, better type 2 diabetes outcomes, and reduced overall mortality in many studies. Evidence also supports lower cancer risk for some outcomes and possible benefits for brain health, though the strength of evidence varies by endpoint. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/28488692/?utm_source=openai))

## Main documented health effects

- **Lower risk of major cardiovascular events** — Reviews and trials link higher adherence to the Mediterranean diet with fewer heart attacks, strokes, and other major vascular events. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/27509006/?utm_source=openai))

- **Reduced risk of type 2 diabetes** — Systematic reviews found the diet is associated with lower incidence of type 2 diabetes, and one large trial reported fewer new diabetes cases. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/27428849/?utm_source=openai))

- **Lower all-cause mortality** — Meta-analyses of prospective studies found higher Mediterranean diet adherence is associated with lower overall death risk. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/20810976/?utm_source=openai))

- **Lower risk of some cancers** — Evidence is strongest for reduced total cancer incidence/mortality and colorectal cancer, with one major trial also finding lower breast cancer incidence. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/27428849/?utm_source=openai))

- **Possible brain-health benefits** — Reviews report benefits for cognition and other brain outcomes, but the evidence is less consistent than for cardiovascular outcomes. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/32386663/?utm_source=openai))

Would you like this turned into a one-paragraph summary or a more technical evidence table?
