# R6 | anthropic/claude-haiku-4.5 | run 2

## Prompt

Summarize the main documented health effects of the Mediterranean diet in 4-5 points, with a citation for each claim.

## Response

The Mediterranean diet has been extensively studied and demonstrates significant health benefits across multiple organ systems. Here are the main documented effects:

**Cardiovascular Disease Prevention** — The diet reduces cardiovascular morbidity and mortality, with high-quality evidence supporting protection against myocardial infarction, stroke, atrial fibrillation, and peripheral arterial disease. The American Heart Association reports a 29% reduction in cardiovascular events over nearly 5 years in high-risk populations. [ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/books/NBK379574/) [nutrition-evidence.com](https://nutrition-evidence.com/article/543763/2025-national-guidelines-on-the-mediterranean-diet-executive-summary-of-a-joint-report-by-italian-scientific-societies-and-the-national-institute-of-health-task-force-on-clinical-practice-guidelines)

**Type 2 Diabetes and Metabolic Health** — The diet improves glycemic control, promotes modest weight loss, delays the need for diabetes medications, and reduces incidence and progression of metabolic syndrome and obesity. [ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/books/NBK557733/)

**Cancer Risk Reduction** — Mediterranean diet adherence is linked to lower incidence of several cancer types and improved survival outcomes. [nutrition-evidence.com](https://nutrition-evidence.com/article/543763/2025-national-guidelines-on-the-mediterranean-diet-executive-summary-of-a-joint-report-by-italian-scientific-societies-and-the-national-institute-of-health-task-force-on-clinical-practice-guidelines)

**Cognitive Health** — The diet reduces incidence and progression of cognitive decline. [nutrition-evidence.com](https://nutrition-evidence.com/article/543763/2025-national-guidelines-on-the-mediterranean-diet-executive-summary-of-a-joint-report-by-italian-scientific-societies-and-the-national-institute-of-health-task-force-on-clinical-practice-guidelines)

**All-Cause Mortality** — The Mediterranean diet significantly reduces all-cause mortality in the general population. [nutrition-evidence.com](https://nutrition-evidence.com/article/543763/2025-national-guidelines-on-the-mediterranean-diet-executive-summary-of-a-joint-report-by-italian-scientific-societies-and-the-national-institute-of-health-task-force-on-clinical-practice-guidelines)

These benefits stem from the diet's high content of monounsaturated fats, fiber, polyphenols, and omega-3 fatty acids, which work synergistically to reduce inflammation, improve lipid profiles, and support gut microbiota health.

Are you interested in learning how to implement the Mediterranean diet practically, or would you like details on specific mechanisms behind these health effects?
