# R6 | x-ai/grok-4.3 | run 2

## Prompt

Summarize the main documented health effects of the Mediterranean diet in 4-5 points, with a citation for each claim.

## Response

The Mediterranean diet is strongly linked to lower risks of major chronic diseases and improved longevity based on extensive observational and trial data. 

Key benefits center on cardiovascular protection, reduced mortality, metabolic improvements, and possible cancer and cognitive advantages. 

## Cardiovascular Protection
Adherence to the Mediterranean diet significantly lowers the risk of major adverse cardiovascular events, myocardial infarction, stroke, and cardiovascular mortality compared to control diets.[[1]](https://pubmed.ncbi.nlm.nih.gov/38431146/)

## Reduced Mortality and Longevity
High adherence is associated with up to a 23% lower risk of all-cause and premature mortality over long-term follow-up in large cohorts.[[2]](https://nutritionsource.hsph.harvard.edu/healthy-weight/diet-reviews/mediterranean-diet/)

## Metabolic Health and Diabetes
It improves metabolic parameters and reduces diabetes risk, with meta-analyses of trials confirming benefits for blood pressure, lipids, and inflammation.[[3]](https://onlinelibrary.wiley.com/doi/10.1111/joim.13333)

## Cancer Outcomes
Greater adherence correlates with lower overall cancer incidence in observational data and reduced mortality among survivors.[[3]](https://onlinelibrary.wiley.com/doi/10.1111/joim.13333)

## Neurodegenerative Disease Risk
Strong evidence links the diet to reduced risk of neurodegenerative diseases such as Alzheimer’s and cognitive decline.[[3]](https://onlinelibrary.wiley.com/doi/10.1111/joim.13333)

What specific aspect of the Mediterranean diet, such as key foods or implementation tips, would you like to explore next?
